MILWAUKEE -- Humberto Quintero and Brandon Lyon were both reeling after Ryan Braun tied the game with a hard slide in the bottom of the ninth.

Houston manager Brad Mills settled them both down in time to come through in extra innings.

Quintero hit a two-out, two-run double in the 10th inning to lift the Astros over the Milwaukee Brewers 9-6 on Saturday night. Quintero's big hit off Sean Green (0-1) came the inning after he couldn't tag Braun quickly enough in a play at the plate that completed Milwaukee's rally from a three-run deficit.

"I'm so happy, you know, the team wins and it's a good win for us," Quintero said. "He pushed my leg and they said he was safe. The last at-bat I got ... I tried to hit it to the middle, and that's what I did."

Houston snapped a four-game losing streak at Miller Park and won its first game when allowing four runs or more this season. It certainly wasn't easy, though.

Lyon (1-1) and the Astros bullpen blew another lead, but Quintero picked the group back up.

Braun hit a two-run homer in the seventh to extend his streak of reaching base safely to 20 games and Prince Fielder added two RBIs to give him an NL-best 21, but it wasn't enough.

Green allowed a double to Brett Wallace with one out in the 10th and intentionally walked Bill Hall.

With two outs, Quintero hit a soaring drive over drawn-in center fielder Carlos Gomez that bounced over the wall to score two. Lyon hit for himself after assuring Mills he'd be ready to pitch another inning, and drove in another run with his first major league hit, a double that dribbled down the third-base line to make it 9-6.

Lyon worked a 1-2-3 10th inning to seal it.

"The way he battled through and pitched both those innings," Mills said, "and you can't say enough about his first major league hit, either."

Milwaukee rallied in the ninth when Braun singled with one out off Lyon, then scored on Fielder's double in the right-field corner. Braun slid hard into Quintero at the plate, beating the tag.

Quintero popped up angrily, arguing to plate umpire Mike Muchinski to no avail. After an out, Lyon went on to load the bases, but got Jonathan Lucroy to ground out weakly to send the game to extra innings.

"The throw was just a little bit off to his right that didn't allow him to get back and get the guy. That's what was tough," Mills said. "The reason I went out there was I wanted to get him calmed down. The last thing we wanted was to lose him in that type of situation."

Astros starter Brett Myers has left every appearance this year with either the lead or the game tied and the bullpen has blown three chances for him to get a victory, just like against the Brewers.

Leading 6-5, Houston got out of a major jam in the eighth when Wallace, the first baseman, collided with reliever Mark Melancon on a bunt that put runners on the corners with no outs. Instead, Milwaukee nearly hit into a triple play because of a pair of baserunning gaffes.

Pinch-hitter Erick Almonte's chopper to third caused Yuniesky Betancourt to stop halfway home.

As he was in the process of being run down and tagged out, Lucroy was leaning too far off second and got caught in a run down himself for a 5-2-6-4-2 double play. After Quintero tagged Lucroy, he fired to Wallace, who would've tagged Almonte out if he'd held on to the ball.

"I was just trying to be aggressive and go to third. But in hindsight it was stupid, I should have stayed at second," Lucroy said. "It was just a mistake."

The wacky play was just a prelude to Lyon's bad ninth.

Down 6-3 in the seventh, Braun hit a two-run, opposite field homer that chased Myers. Braun would come up big again, setting the stage for Milwaukee's frantic ninth-inning rally.

"We did a great job of battling back," Brewers manager Ron Roenicke said. "We were a base-hit away from winning the ballgame. I was happy with the way we came back. It's a tough game to lose."

Game notes
Carlos Lee hit a two-run homer in the first and Hunter Pence added a solo shot in the third. ... The Astros also scored twice off reliever Brandon Kintzler in the seventh. ... Brewers 2B Rickie Weeks (sprained left pinkie) wasn't in the starting lineup. He expects to return Sunday.