White Sox starter Mark Buehrle (5-4) pitched six effective innings. He allowed three runs while giving up 10 hits, striking out four with just one walk.

With one out in the eighth, reliever Matt Thornton gave up three consecutive singles. He was helped by Pierre, who made a running catch into the left-field fence to take away an extra base hit from Alex Avila. Victor Martinez tagged from third to cut the Chicago lead to 5-4.

After the spectacular catch, Pierre hit a leadoff homer in the eighth to put Chicago up 6-4. It was the 11-year veteran's first home run since Aug. 3, 2010, against Detroit.

Pierre got off to a slow start at the plate in April and also dropped a crucial fly ball with Thornton on the mound that led to the tying run in a 2-1 loss to the Athletics on April 11.

"For some reason, the last couple of years in April, Juan struggled on the field, offensively and defensively," Guillen said. "I keep saying, 'Never give up on Juan.' Never will. The guy works hard, he shows up everyday to win. He is going to be in the lineup no matter what and that's what he's done throughout his career."

White Sox closer Sergio Santos struck out Ramon Santiago with runners on first and second in the eighth, then pitched a scoreless ninth for his 10th save in 11 opportunities. He got Miguel Cabrera swinging to end the game with a runner on second.

Guillen wanted to challenge Cabrera with Martinez on-deck.

"Martinez was laughing in the on-deck circle because he thought we were going to walk him (Cabrera) but I respect Victor. Victor is a dangerous hitter. I'm not going to put the go-ahead run at the plate, especially with Victor Martinez," Guillen said.

Brent Lillibridge also added a solo shot for the White Sox.

Casper Wells hit a three-run homer for Detroit, which was trying to win 10 straight games against the White Sox for the first time since 1923.

Leading 1-0 in the fourth, the White Sox finally knocked out Detroit starter Andrew Oliver, who was flirting with trouble his entire start.

Oliver allowed his fifth walk of the game when Pierre reached with two outs, then Alexei Ramirez followed with a single. Quentin gave the White Sox a 4-0 lead with his 14th homer of the season into the left-field bullpen. A.J. Pierzynski quickly ended Oliver's night with a double.

"It was just a struggle from the first batter. I struggled with the command on my fastball," said Oliver. "It's just getting ahead of guys. You'll be a lot more effective that way."

Oliver (0-1) allowed four runs in his second start for the injured Phil Coke.

"We were dodging bullets the whole game, really. Oliver was unable to locate the strike zone," said Tigers manager Jim Leyland.

Lillibridge tagged Charlie Furbush with a solo shot leading off the fifth to give the White Sox a 5-3 lead. Lillibridge, who came into the season with three career home runs, now has seven on the season. He has homered four times in his last 13 games.

Danny Worth and Austin Jackson had back-to-back singles against Buehrle in the fifth, and Detroit got on the board after Wells drove Buehrle's pitch into the left-center bleachers for a three-run shot. It was Wells' second of season.

The White Sox had runners on second and third with no outs in the third and couldn't score. Alex Rios popped out to shallow left field, Lillibridge struck out and Adam Dunn grounded out to first base to a loud chorus of boos.

After Lillibridge's home run in the fifth, the White Sox failed to score with bases loaded a no outs. Pierre's grounder forced Dunn out at the plate and Ramirez hit into a double play.

"Early in the game, I thought this kid (Oliver) wasn't going to come out for the second inning, then all of a sudden, we didn't take advantage of the situation," Guillen said. "We made it a little tougher at the end of the game because we didn't get the big hits early."

Game notes
The White Sox are done waiting for Dunn to break out of his season-long slump. "Well, we're not waiting for him. You can't wait for anyone to break out," said general manager Ken Williams. Dunn ended an 0-for-40 skid against left-handers with an infield single against Furbush in the fifth. ... Dunn was in the lineup because Paul Konerko was late scratched after having a minor medical procedure to dislodge a loose fragment in his left wrist. The White Sox don't expect Konerko to miss anymore time. ... Tigers 3B Brandon Inge went on the DL with mononucleosis. ... The White Sox were 2 for 12 with runners in scoring position.